INF 4E

Tocris Bioscience, part of Bio-Techne | Catalog # 6172

Caspase-1 and NLRP3 inflammasome inhibitor
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Key Product Details

Description

Caspase-1 and NLRP3 inflammasome inhibitor

View all Inflammasomes Inhibitors »

Product Description

INF 4E is a NLRP3 inflammasome and caspase-1 inhibitor (Ki = 9.6 μM for caspase-1). Inhibits Nigericin (Cat. No. 4312) or ATP (Cat.No. 3245) induced pyroptosis of PMA-differentiated and LPS-primed THP-1 cells and activates the Keap1-Nrf2 pathway.

Product Specifications

Molecular Weight

240.68

Formula

C12H13ClO3

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate

CAS Number

88039-46-7

PubChem ID

11402215

InChI Key

BSRPDXCMAOIUOO-UHFFFAOYSA-N

SMILES

CCOC(C(C(C1=C(C=CC=C1)Cl)O)=C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble in DMSO (supplied pre-dissolved in DMSO, 10mg/ml)

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Background References

References are publications that support the biological activity of the product.

Product Documents for INF 4E

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for INF 4E

For research use only

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