Immethridine dihydrobromide

Tocris Bioscience, part of Bio-Techne | Catalog # 2315

Potent H3 agonist, highly selective over H4
Discontinued Product
2315 has been discontinued. View all Histamine H3 Receptor Agonists products.

Key Product Details

Description

Potent H3 agonist, highly selective over H4

View all Histamine H3 Receptor Agonists »

Product Description

Immethridine dihydrobromide is a potent and highly selective histamine H3 receptor agonist (pEC50 = 9.74) that displays 300-fold selectivity over the H4 receptor (pKi values are 9.07 and 6.61 respectively). Does not bind to H1 or H2 receptors at concentrations up to 10 μM. .

Product Specifications

Molecular Weight

321.01

Formula

C9H9N3.2HBr

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

4-(1H-Imidazol-4-ylmethyl)pyridine dihydrobromide

CAS Number

699020-93-4

PubChem ID

16759172

InChI Key

CYNKWHIKNDIVDR-UHFFFAOYSA-N

SMILES

Br.Br.C(C1=CN=CN1)C1=CC=NC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 32.1 100

Preparing Stock Solutions for Immethridine dihydrobromide

The following data is based on the product molecular weight 321.01

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.12 mL 15.58 mL 31.15 mL
5 mM 0.62 mL 3.12 mL 6.23 mL
10 mM 0.31 mL 1.56 mL 3.12 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Immethridine dihydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Immethridine dihydrobromide

For research use only

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