Furanone C-30
Tocris Bioscience, part of Bio-Techne | Catalog # 6546
Quorum sensing inhibitor; antibacterial
Discontinued Product
6546 has been discontinued.
View all Antibiotics products.
Product Description
Furanone C-30 is a synthetic furanone bacterial quorum sensing inhibitor. Inhibits virulence factor expression in Pseudomonas aeruginosa and increases bacterial susceptibility to antibiotics in vitro. Also inhibits bacterial quorum sensing in vivo and promotes bacterial clearance in a mouse pulmonary infection model.Product Specifications
Molecular Weight
253.88
Formula
C5H2Br2O2
Storage
Store at -20°C
Purity
≥98%
Chemical Name
(5Z)-4-Bromo-5-(bromomethylene)-2(5H)-furanone
CAS Number
247167-54-0
PubChem ID
67228456
InChI Key
DPGLBHQUHFJRJS-UHFFFAOYSA-N
SMILES
Br/C=C1OC(C=C\1Br)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 25.39 | 100 |
Preparing Stock Solutions
for Furanone C-30
The following data is based on the product molecular weight 253.88
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.94 mL | 19.69 mL | 39.39 mL |
| 5 mM | 0.79 mL | 3.94 mL | 7.88 mL |
| 10 mM | 0.39 mL | 1.97 mL | 3.94 mL |
| 50 mM | 0.08 mL | 0.39 mL | 0.79 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hentzer Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 2003 PMID: 12881415
Product Specific Notices for Furanone C-30
For research use only
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