FPA 124

Name: FPA 124
Brand: Tocris Bioscience
SKU: 2926

Tocris Bioscience, part of Bio-Techne | Catalog # 2926

Citations (9)

COA / SDS

Akt/PKB inhibitor

Discontinued Product

2926 has been discontinued. View all Akt (Protein Kinase B) Inhibitors products.

Key Product Details

Description:	Akt/PKB inhibitor
Chemical Name:	Dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide copper complex
Molecular Weight:	381.73

View Full Technical Details for FPA 124

Technical Data
Citations

Biological Activity for FPA 124

FPA 124 is an Akt/PKB inhibitor (IC₅₀ = 100 nM) that interacts with the PH and kinase domains. Inhibits cell proliferation in various cancer cell lines in vitro and decreases NF-κB activity and tumor load in vivo.

Technical Data for FPA 124

M. Wt	381.73
Formula	C₁₁H₉Cl₂CuN₃O₂S
Storage	Store at +4°C
CAS Number	902779-59-3
PubChem ID	16034833
InChi Key	HZRXQEVFXXQYFS-VBPDOGLUSA-L
Smiles	Cl[Cu]Cl.NC(=S)N\N=C\C1=COC2=C(C=CC=C2)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for FPA 124

References are publications that support the biological activity of the product.

Barve Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells. J.Med.Chem. 2006 PMID: 16789737

FPA 124

Tocris Bioscience, part of Bio-Techne | Catalog # 2926

Key Product Details

Biological Activity for FPA 124

Technical Data for FPA 124

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for FPA 124

Product Documents for FPA 124

COA

Certificate of Analysis

SDS

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