Fenoldopam hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 1659
Selective D1-like partial agonist
Key Product Details
Description
Selective D1-like partial agonist
Alternative Names
SKF 82526
Product Description
Fenoldopam hydrochloride is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM). Vasodilator in vivo and does not readily cross the blood-brain barrier. Also α2-adrenoceptor antagonist in vitro (Ki = 15 - 25 nM).Licensing Information
Sold for research purposes under agreement from GlaxoSmithKlineProduct Specifications
Molecular Weight
342.22
Formula
C16H16ClNO3.HCl
Storage
Desiccate at +4°C
Purity
≥98% (HPLC)
Chemical Name
6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol hydrochloride
CAS Number
181217-39-0
PubChem ID
21642479
InChI Key
NLMPGIXLXSPNFS-UHFFFAOYSA-N
SMILES
Cl.OC1=CC=C(C=C1)C1CNCCC2=C(Cl)C(O)=C(O)C=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 3.06 | 10 |
Preparing Stock Solutions
for Fenoldopam hydrochloride
The following data is based on the product molecular weight 342.22
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.22 mL | 146.10 mL | 292.21 mL |
| 0.5 mM | 5.84 mL | 29.22 mL | 58.44 mL |
| 1 mM | 2.92 mL | 14.61 mL | 29.22 mL |
| 5 mM | 0.58 mL | 2.92 mL | 5.84 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Nichols The pharmacology of fenol. Am.J.Hypertens. 1990 PMID: 1974439
- Sibley Interactions of novel DArgic ligands with D-1 and D-2 DA receptors. Life Sci. 1982 PMID: 6127585
- Hahn Characterization of the peripheral and central effects of SK&F 82526, a novel DA receptor agonist. J.Pharmacol.Exp.Ther. 1982 PMID: 6127401
Product Specific Notices for Fenoldopam hydrochloride
For research use only
Loading...
Loading...