Epoprostenol
Tocris Bioscience, part of Bio-Techne | Catalog # 2989
Endogenous IP receptor agonist
Key Product Details
Description
Endogenous IP receptor agonist
Alternative Names
Prostaglandin I2,Prostacyclin
Product Description
Epoprostenol is an endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.Product Specifications
Molecular Weight
374.45
Formula
C20H31NaO5
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
CAS Number
61849-14-7
PubChem ID
6364626
InChI Key
LMHIPJMTZHDKEW-XQYLJSSYSA-M
SMILES
[Na+].CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2O\C(C[C@H]12)=C/CCCC([O-])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 37.44 | 100 |
Preparing Stock Solutions
for Epoprostenol
The following data is based on the product molecular weight 374.45
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.67 mL | 13.35 mL | 26.71 mL |
| 5 mM | 0.53 mL | 2.67 mL | 5.34 mL |
| 10 mM | 0.27 mL | 1.34 mL | 2.67 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.53 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Oliva and Nicosia PGI2-receptors and molecular mechanisms in platelets and vasculature: state of the art. Pharmacol.Res.Comm.
- Kobzar Comparison of anti-aggregatory effects of PGI2, PGI3 and ilo. on human and rabbit platelets. Cell.Physiol.Biochem. 2001 PMID: 11684817
Product Specific Notices for Epoprostenol
For research use only
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