DPTN

Tocris Bioscience, part of Bio-Techne | Catalog # 7628

Potent and selective A3 adenosine receptor antagonist
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Key Product Details

Description

Potent and selective A3 adenosine receptor antagonist

View all Adenosine A3 Receptor Antagonists »

Product Description

DPTN is a potent and selective A3 adenosine receptor antagonist (Ki values are in the range 0.36 - 1.65 nM (hA3AR) and 1.6 - 8.53 nM (rA3AR)). Reduces intrapulmonary pressure when combined with Dexamethasone (Cat. No. 1126). Readily crosses the blood brain barrier in rats.

Product Specifications

Molecular Weight

459.39

Formula

C22H18N4OS.2HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[4-(3,5-Dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-3-pyridinecarboxamide dihydrochloride

CAS Number

325767-87-1

InChI Key

GTWKWBXTCBUKTR-UHFFFAOYSA-N

SMILES

CC1=CC(C2=C(C3=CC=NC=C3)SC(NC(C4=CN=CC=C4)=O)=N2)=CC(C)=C1.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 9.19 20 with gentle warming

Preparing Stock Solutions for DPTN

The following data is based on the product molecular weight 459.39

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 10.88 mL 54.42 mL 108.84 mL
1 mM 2.18 mL 10.88 mL 21.77 mL
2 mM 1.09 mL 5.44 mL 10.88 mL
10 mM 0.22 mL 1.09 mL 2.18 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for DPTN

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DPTN

For research use only

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