DNQX
Tocris Bioscience, part of Bio-Techne | Catalog # 0189
Selective non-NMDA iGluR antagonist
Key Product Details
Description
Selective non-NMDA iGluR antagonist
Product Description
DNQX is a selective non-NMDA receptor antagonist.Water-soluble Salt also available.
Product Specifications
Molecular Weight
252.14
Formula
C8H4N4O6
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
6,7-Dinitroquinoxaline-2,3-dione
CAS Number
2379-57-9
PubChem ID
3899541
InChI Key
RWVIMCIPOAXUDG-UHFFFAOYSA-N
SMILES
[O-][N+](=O)C1=C(C=C2NC(=O)C(=O)NC2=C1)[N+]([O-])=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 25.21 | 100 |
Preparing Stock Solutions
for DNQX
The following data is based on the product molecular weight 252.14
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.97 mL | 19.83 mL | 39.66 mL |
| 5 mM | 0.79 mL | 3.97 mL | 7.93 mL |
| 10 mM | 0.40 mL | 1.98 mL | 3.97 mL |
| 50 mM | 0.08 mL | 0.40 mL | 0.79 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Watkins Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. TiPS 1990 PMID: 2155495
- Honore Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science 1988 PMID: 2899909
Product Specific Notices for DNQX
For research use only
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