DLPC
Tocris Bioscience, part of Bio-Techne | Catalog # 4378
LRH-1 agonist; regulates bile acid metabolism
Discontinued Product
4378 has been discontinued.
View all Other Nuclear Receptor Agonists products.
Key Product Details
Description
LRH-1 agonist; regulates bile acid metabolism
Product Description
Selective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro. Induces bile acid biosynthetic enzymes; increases bile acid and decreases hepatic triglycerides and serum glucose. Exhibits antidiabetic effects.Product Specifications
Molecular Weight
621.83
Formula
C32H64NO8P
Storage
Store at -20°C
Chemical Name
(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide
CAS Number
18194-25-7
PubChem ID
512874
InChI Key
IJFVSSZAOYLHEE-SSEXGKCCSA-N
SMILES
[O-]P(OC[C@H](OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)(OCC[N+](C)(C)C)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| Ethanol | 62.18 | 100 |
Preparing Stock Solutions
for DLPC
The following data is based on the product molecular weight 621.83
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.61 mL | 8.04 mL | 16.08 mL |
| 5 mM | 0.32 mL | 1.61 mL | 3.22 mL |
| 10 mM | 0.16 mL | 0.80 mL | 1.61 mL |
| 50 mM | 0.03 mL | 0.16 mL | 0.32 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Lee A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature 2011 PMID: 21614002
Product Specific Notices for DLPC
For research use only
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