DLin-KC2-DMA
Tocris Bioscience, part of Bio-Techne | Catalog # 8895
Ionizable cationic lipid
Product Description
DLin-KC2-DMA is an ionizable cationic lipid (pKa = 6.7), used in the formulation of lipid nanoparticles (LNPs) encapsulating siRNA or plasmid DNA for non-toxic delivery into cells in vitro and in vivo.This product is supplied pre-dissolved in anhydrous ethanol, 100mg/mL
For more information on LNPs and available components see our Lipid Nanoparticles page.
Product Specifications
Molecular Weight
642.11
Formula
C43H79NO2
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
2-[2,2-Di-[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
CAS Number
1190197-97-7
PubChem ID
44464860
InChI Key
LRFJOIPOPUJUMI-KWXKLSQISA-N
SMILES
C(CCCCCCC/C=C\C/C=C\CCCCC)C1(CCCCCCCC/C=C\C/C=C\CCCCC)OC(CCN(C)C)CO1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 100mg/mL) |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kulkarni Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine 2017 PMID: 28038954
Product Specific Notices for DLin-KC2-DMA
For research use only
Loading...
Loading...