(±)-Vesamicol hydrochloride

Name: (±)-Vesamicol hydrochloride
Brand: Tocris Bioscience
SKU: 0653

Tocris Bioscience, part of Bio-Techne | Catalog # 0653

COA / SDS

Inhibits ACh transport

Discontinued Product

0653 has been discontinued. View all Acetylcholine Transporter Inhibitors products.

Key Product Details

Description:	Inhibits ACh transport
Alternative Names:	AH 5183
Chemical Name:	(±)-trans-2-(4-Phenylpiperidinyl)cyclohexanol hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	295.85

View Full Technical Details for (±)-Vesamicol hydrochloride

Technical Data
Citations

Biological Activity for (±)-Vesamicol hydrochloride

(±)-Vesamicol hydrochloride is an inhibitor of acetylcholine transport (K_i = 2 nM). Centrally active following systemic administration in vivo.

Technical Data for (±)-Vesamicol hydrochloride

M. Wt	295.85
Formula	C₁₇H₂₅NO.HCl
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	120447-62-3
PubChem ID	659839
InChi Key	XJNUHVMJVWOYCW-GBNZRNLASA-N
Smiles	O[C@@H]1CCCC[C@H]1N(CC3)CCC3C2=CC=CC=C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for (±)-Vesamicol hydrochloride

References are publications that support the biological activity of the product.

Kobayashi Effects of systemic administration of 2-(4-phenyl-piperidino)-cyclohexanol (vesamicol) and an organophosphate DDVP on the cholinergic system in brain regions of rats. Brain Res.Bull. 1997 PMID: 9205789
Varoqui and Erickson Active transport of acetylcholine by the human vesicular acetylcholine transporter. J.Biol.Chem. 1996 PMID: 8910293
Efange N-hydroxyalkyl derivatives of 3β-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. J.Med.Chem. 1997 PMID: 9397171

(±)-Vesamicol hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0653

Key Product Details

Biological Activity for (±)-Vesamicol hydrochloride

Technical Data for (±)-Vesamicol hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for (±)-Vesamicol hydrochloride

Product Documents for (±)-Vesamicol hydrochloride

COA

Certificate of Analysis

SDS

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