DL-AP4

Name: DL-AP4
Brand: Tocris Bioscience
SKU: 0101

Tocris Bioscience, part of Bio-Techne | Catalog # 0101

Citations (78)

COA / SDS

Broad spectrum glutamatergic antagonist

Key Product Details

Description:	Broad spectrum glutamatergic antagonist
Chemical Name:	DL-2-Amino-4-phosphonobutyric acid
Purity:	≥98% (HPLC)
Molecular Weight:	183.1

View Full Technical Details for DL-AP4

Technical Data
Citations

Biological Activity for DL-AP4

DL-AP4 is a broad spectrum EAA ligand.

L-isomer also available.

Technical Data for DL-AP4

M. Wt	183.1
Formula	C₄H₁₀NO₅P
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	6323-99-5
PubChem ID	2207
InChi Key	DDOQBQRIEWHWBT-UHFFFAOYSA-N
Smiles	O=C(C(N)CCP(O)(O)=O)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for DL-AP4

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	9.15	50

Preparing Stock Solutions for DL-AP4

The following data is based on the product molecular weight 183.1.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	10.92 mL	54.61 mL	109.23 mL
2.5 mM	2.18 mL	10.92 mL	21.85 mL
5 mM	1.09 mL	5.46 mL	10.92 mL
25 mM	0.22 mL	1.09 mL	2.18 mL

Molarity Calculator

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Reconstitution Calculator

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References for DL-AP4

References are publications that support the biological activity of the product.

Evans The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 1982 PMID: 7042024
Evans Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog. Br.J.Pharmacol. 1979 PMID: 316343