(±)-Anatoxin A fumarate

Tocris Bioscience, part of Bio-Techne | Catalog # 0789

nAChR agonist
Discontinued Product
0789 has been discontinued. View all Additional Nicotinic Receptor Agonists products.

Key Product Details

Description

nAChR agonist

View all Additional Nicotinic Receptor Agonists »

Product Description

(±)-Anatoxin A fumarate is a potent nicotinic agonist (Ki values are 1.25 and 1840 nM for α4β2 and α7 nicotinic receptors respectively). (±)-Anatoxin A fumarate stimulates [3H]-dopamine release from rat striatal synaptosomes (EC50 = 136 nM). (±)-Anatoxin A fumarate induces apoptosis in rat thymocytes and Vero cells by generation of reactive oxygen species and caspase activation.

Product Specifications

Molecular Weight

281.31

Formula

C10H15NO.C4H4O4

Storage

Store at +4°C

Purity

≥96% (HPLC)

Chemical Name

(±)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate

CAS Number

1219922-30-1

PubChem ID

45073416

InChI Key

ZJSIFVODFDHYJU-WLHGVMLRSA-N

SMILES

O=C(C)C1=CCCC2CCC1N2.O=C(O)/C=C/C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 28.13 100

Preparing Stock Solutions for (±)-Anatoxin A fumarate

The following data is based on the product molecular weight 281.31

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.55 mL 17.77 mL 35.55 mL
5 mM 0.71 mL 3.55 mL 7.11 mL
10 mM 0.36 mL 1.78 mL 3.55 mL
50 mM 0.07 mL 0.36 mL 0.71 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (±)-Anatoxin A fumarate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (±)-Anatoxin A fumarate

For research use only

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