DIPPA hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0794
Selective and irreversible κ antagonist
Key Product Details
Description
Selective and irreversible κ antagonist
Product Description
DIPPA hydrochloride is an an irreversible and selective antagonist at the κ receptor, with persistent effect in vivo.Product Specifications
Molecular Weight
484.87
Formula
C22H23Cl2N3OS.HCl
Storage
Desiccate at -20°C
Purity
≥98% (HPLC)
Chemical Name
2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride
CAS Number
155512-52-0
PubChem ID
45073425
InChI Key
BNWYENYHNOESCX-ZMBIFBSDSA-N
SMILES
ClC1=C(Cl)C=C(CC(N([C@@](CN3CCCC3)([H])C2=CC=CC(N=C=S)=C2)C)=O)C=C1.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.24 | 50 | |
| Ethanol | 14.55 | 30 |
Preparing Stock Solutions
for DIPPA hydrochloride
The following data is based on the product molecular weight 484.87
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.12 mL | 20.62 mL | 41.25 mL |
| 2.5 mM | 0.82 mL | 4.12 mL | 8.25 mL |
| 5 mM | 0.41 mL | 2.06 mL | 4.12 mL |
| 25 mM | 0.08 mL | 0.41 mL | 0.82 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Chang κ opioid receptor selective affinity labels: Electrophilic benzeneacetamides as κ-selective opioid antagonists. J.Med.Chem. 1994 PMID: 7799399
- Chang 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide: an opioid receptor affinity label that produces selective and long lasting κ antagonism in mice. J.Med.Chem. 1994 PMID: 8201586
Product Specific Notices for DIPPA hydrochloride
For research use only
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