Dilazep dihydrochloride

Name: Dilazep dihydrochloride
Brand: Tocris Bioscience
SKU: 0481

Tocris Bioscience, part of Bio-Techne | Catalog # 0481

Citations (1)

COA / SDS

Adenosine uptake inhibitor

Key Product Details

Description:	Adenosine uptake inhibitor
Chemical Name:	1,4-bis[3-(3,4,5-Trimethoxybenzoyloxy)propyl]homopiperazine dihydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	677.62

View Full Technical Details for Dilazep dihydrochloride

Technical Data
Citations

Biological Activity for Dilazep dihydrochloride

Dilazep dihydrochloride is a coronary and cerebral vasodilator, suppresses the effects of ischemia. Inhibitor of platelet aggregation and of membrane transport of nucleosides. Inhibits adenosine uptake.

Technical Data for Dilazep dihydrochloride

M. Wt	677.62
Formula	C₃₁H₄₄N₂O₁₀.2HCl
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	20153-98-4
PubChem ID	29976
InChi Key	VILIWRRWAWKXRW-UHFFFAOYSA-N
Smiles	Cl.Cl.COC1=CC(=CC(OC)=C1OC)C(=O)OCCCN1CCCN(CCCOC(=O)C2=CC(OC)=C(OC)C(OC)=C2)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Dilazep dihydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water		100

Preparing Stock Solutions for Dilazep dihydrochloride

The following data is based on the product molecular weight 677.62.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.48 mL	7.38 mL	14.76 mL
5 mM	0.30 mL	1.48 mL	2.95 mL
10 mM	0.15 mL	0.74 mL	1.48 mL
50 mM	0.03 mL	0.15 mL	0.30 mL

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Reconstitution Calculator

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References for Dilazep dihydrochloride

References are publications that support the biological activity of the product.

Zhang Dilazep potentation of adenosine-mediated superior mesenteric arterial vasodilation. J.Pharmacol.Exp.Ther. 1991 PMID: 1890619
Kawagoe Effect of dilazep dihydrochloride against ischemia and reperfusion-induced disruption of blood-brain barrier in rats: a quantitative study. Naunyn Schmiedebergs Arch.Pharmacol. 1992 PMID: 1620248