DC 260126

Tocris Bioscience, part of Bio-Techne | Catalog # 5357

FFA1 (GPR40) antagonist
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Key Product Details

Description

FFA1 (GPR40) antagonist

View all Free Fatty Acid Receptor Antagonists »

Product Description

DC 260126 is a free fatty acid receptor 1 (FFA1/GPR40) antagonist. Inhibits FFA-induced increases in intracellular Ca2+ levels and suppresses palmitic acid potentiated glucose-stimulated insulin secretion in Min6 pancreatic β cells in vitro. Decreases serum insulin levels, improves insulin sensitivity and reduces the number of apoptotic pancreatic β cells in obese diabetic (db/db) rats.

Product Specifications

Molecular Weight

307.38

Formula

C16H18FNO2S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-(4-Butylphenyl)-4-fluorobenzenesulfonamide

CAS Number

346692-04-4

PubChem ID

2843133

InChI Key

CNGHPXKWPGIDSK-UHFFFAOYSA-N

SMILES

CCCCC(C=C2)=CC=C2NS(C1=CC=C(F)C=C1)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.74 100
Ethanol 30.74 100

Preparing Stock Solutions for DC 260126

The following data is based on the product molecular weight 307.38

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.25 mL 16.27 mL 32.53 mL
5 mM 0.65 mL 3.25 mL 6.51 mL
10 mM 0.33 mL 1.63 mL 3.25 mL
50 mM 0.07 mL 0.33 mL 0.65 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for DC 260126

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DC 260126

For research use only

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