CyPPA
Tocris Bioscience, part of Bio-Techne | Catalog # 2953
KCa2.2 and KCa2.3 (SK) channel activator
Key Product Details
Description
KCa2.2 and KCa2.3 (SK) channel activator
Product Description
CyPPA is an activator of small conductance Ca2+-activated K+ channels that displays selectivity for KCa2.2 (SK2) and KCa2.3 (SK3) channels (EC50 values are 5.6 and 14 μM for KCa2.3 and KCa2.2 respectively). Displays no activity at KCa2.1 (SK1) and KCa3.1 (IK) channels.Product Specifications
Molecular Weight
285.39
Formula
C16H23N5
Storage
Store at +4°C
Purity
≥99% (HPLC)
Chemical Name
N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine
CAS Number
73029-73-9
PubChem ID
909822
InChI Key
USEMRPYUFJNFQN-UHFFFAOYSA-N
SMILES
CC1=NC(N2N=C(C)C=C2C)=NC(NC3CCCCC3)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hougaard Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels. Br.J.Pharmacol. 2007 PMID: 17486140
Product Specific Notices for CyPPA
For research use only
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