CYM 50260
Tocris Bioscience, part of Bio-Techne | Catalog # 4677
Potent and selective S1P4 agonist
Key Product Details
Description
Potent and selective S1P4 agonist
Product Description
CYM 50260 is a potent sphingosine-1-phosphate receptor 4 (S1P4) agonist (EC50 = 45 nM). Displays no activity at other S1P receptor subtypes (S1P1-3 and S1P5) at concentrations up to 25 μM.Product Specifications
Molecular Weight
350.60
Formula
C14H11Cl3FNO2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
2-Chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)pyridine
CAS Number
1355026-60-6
PubChem ID
44620894
InChI Key
FHPOTBQOUBMMCI-UHFFFAOYSA-N
SMILES
ClC1=CC(Cl)=C(OCCOC2=CC=C(CF)N=C2Cl)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 35.06 | 100 |
Preparing Stock Solutions
for CYM 50260
The following data is based on the product molecular weight 350.60
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.85 mL | 14.26 mL | 28.52 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.70 mL |
| 10 mM | 0.29 mL | 1.43 mL | 2.85 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.57 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Guerrero Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists. Bioorg.Med.Chem.Lett. 2011 PMID: 22119461
Product Specific Notices for CYM 50260
For research use only
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