CX 546

Tocris Bioscience, part of Bio-Techne | Catalog # 2980

AMPA potentiator
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Key Product Details

Description

AMPA potentiator

View all AMPA Receptor Modulators »

Product Description

CX 546 is an AMPA receptor potentiator. Binds specifically to the agonist bound non-desensitized receptor, most likely destabilizing the desensitized receptor conformation. Enhances cognitive function in rats. Neuroprotective in mice undergoing repeat ketamine anesthesia.

Product Specifications

Molecular Weight

247.29

Formula

C14H17NO3

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone

CAS Number

215923-54-9

PubChem ID

2890

InChI Key

LJUNPHMOGNFFOS-UHFFFAOYSA-N

SMILES

O=C(N3CCCCC3)C2=CC1=C(C=C2)OCCO1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 24.73 100
Ethanol 24.73 100

Preparing Stock Solutions for CX 546

The following data is based on the product molecular weight 247.29

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.04 mL 20.22 mL 40.44 mL
5 mM 0.81 mL 4.04 mL 8.09 mL
10 mM 0.40 mL 2.02 mL 4.04 mL
50 mM 0.08 mL 0.40 mL 0.81 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for CX 546

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CX 546

For research use only

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