CRF (6-33)
Tocris Bioscience, part of Bio-Techne | Catalog # 1607
CRF-binding protein inhibitor
Discontinued Product
1607 has been discontinued.
View all Additional Non-selective CRF Receptor Products products.
Key Product Details
Description
CRF-binding protein inhibitor
Alternative Names
Corticotropin-Releasing Factor (6-33)
Product Description
CRF (6-33) is a corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.Licensing Information
Sold with the permission of the SALK InstituteProduct Specifications
Molecular Weight
3220.68
Formula
C141H231N41O43S
Storage
Desiccate at -20°C
CAS Number
120066-38-8
PubChem ID
16135485
InChI Key
XHHPINGDTRCKNN-QZXFXOMNSA-N
SMILES
[H]N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Heinrichs Selective stimulatory actions of corticotropin-releasing factor ligands on correlates of energy balance. Physiol.Behav. 2001 PMID: 11564446
- Jahn The binding protein of corticotropin-releasing factor: ligand-binding site and subunit structure. Proc.Natl.Acad.Sci.U.S.A. 2002 PMID: 12215497
- Heinrichs Dissociation of arousal-like from anxiogenic-like actions of brain corticotropin-releasing factor receptor ligands in rats. Behav.Brain Res. 2001 PMID: 11287075
Product Specific Notices for CRF (6-33)
For research use only
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