CP 94253 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 1317
Potent and selective 5-HT1B agonist
Key Product Details
Description
Potent and selective 5-HT1B agonist
Product Description
CP 94253 hydrochloride is a potent, selective 5-HT1B agonist (Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively). Centrally active upon systemic administration in vivo.Product Specifications
Molecular Weight
293.80
Formula
C15H19N3O.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride
CAS Number
845861-39-4
PubChem ID
11652258
InChI Key
PIIOXKQIZCVXMD-UHFFFAOYSA-N
SMILES
Cl.CCCOC1=CC=C2NC=C(C2=N1)C1=CCNCC1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 7.34 | 25 | |
| DMSO | 29.38 | 100 |
Preparing Stock Solutions
for CP 94253 hydrochloride
The following data is based on the product molecular weight 293.80
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.40 mL | 17.02 mL | 34.04 mL |
| 5 mM | 0.68 mL | 3.40 mL | 6.81 mL |
| 10 mM | 0.34 mL | 1.70 mL | 3.40 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.68 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Knobelman Regulation of extracellular concentrations of 5-hydroxytryptamine (5-HT) in mouse striatum by 5-HT1A and 5-HT1B receptors. J.Pharmacol.Exp.Ther. 2000 PMID: 10688630
- Koe Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253. Drug Dev.Res.
- Fish Aggression heightened by alcohol or social instigation in mice: reduction by the 5-HT(1B) receptor agonist CP-94,253. Psychopharmacology 1999 PMID: 10550489
Product Specific Notices for CP 94253 hydrochloride
For research use only
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