CM 10

Tocris Bioscience, part of Bio-Techne | Catalog # 6933

ALDH1A inhibitor; depletes CD133+ cancer stem cells
Discontinued Product
6933 has been discontinued. View all Aldehyde Dehydrogenase Inhibitors products.

Key Product Details

Description

ALDH1A inhibitor; depletes CD133+ cancer stem cells

View all Aldehyde Dehydrogenase Inhibitors »

Product Description

CM 10 is a aldehyde dehydrogenase 1A (ALDH1A) inhibitor (IC50 values are 0.64, 0.74 and 1.7 μM for ALDH1A3, ALDH1A2 and ALDH1A1, respectively). Induces a necroptotic phenotype and preferentially depletes CD133+ ovarian cancer stem cells in vitro.

Product Specifications

Molecular Weight

321.42

Formula

C20H23N3O

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol

CAS Number

692269-09-3

PubChem ID

889692

InChI Key

ZFHWEWJDCFGRBO-UHFFFAOYSA-N

SMILES

CCCN1C(NCC2=C(O)C(CC=C)=CC=C2)=NC2=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.14 100

Preparing Stock Solutions for CM 10

The following data is based on the product molecular weight 321.42

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.11 mL 15.56 mL 31.11 mL
5 mM 0.62 mL 3.11 mL 6.22 mL
10 mM 0.31 mL 1.56 mL 3.11 mL
50 mM 0.06 mL 0.31 mL 0.62 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for CM 10

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CM 10

For research use only

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