Clomipramine hydrochloride

Name: Clomipramine hydrochloride
Brand: Tocris Bioscience
SKU: 0457

Tocris Bioscience, part of Bio-Techne | Catalog # 0457

Citations (4)

COA / SDS

5-HT reuptake inhibitor

Discontinued Product

0457 has been discontinued. View all 5-HT Transporter Inhibitors products.

Key Product Details

Description:	5-HT reuptake inhibitor
Chemical Name:	3-Chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	351.32

View Full Technical Details for Clomipramine hydrochloride

Technical Data
Citations

Biological Activity for Clomipramine hydrochloride

Clomipramine hydrochloride is a potent, selective 5-HT uptake blocker. Antidepressant. Binds to the human 5-HT transporter with a K_i of 0.05 nmol/l.

Technical Data for Clomipramine hydrochloride

M. Wt	351.32
Formula	C₁₉H₂₃ClN₂.HCl
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	17321-77-6
PubChem ID	68539
InChi Key	WIMWMKZEIBHDTH-UHFFFAOYSA-N
Smiles	Cl.CN(C)CCCN1C2=CC(Cl)=CC=C2CCC2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Clomipramine hydrochloride

References are publications that support the biological activity of the product.

Ortiz and Artiga Effects of monoamine uptake inhibitors on extracellular and platelet 5-hydroxytryptamine in rat blood: different effects of clomipramine and fluox. Br.J.Pharmacol. 1992 PMID: 1387022
Owens Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J.Pharmacol.Exp.Ther. 1997 PMID: 9400006
McTavish and Benfield Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs 1990 PMID: 2178909

Clomipramine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0457

Key Product Details

Biological Activity for Clomipramine hydrochloride

Technical Data for Clomipramine hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Clomipramine hydrochloride

Product Documents for Clomipramine hydrochloride

COA

Certificate of Analysis

SDS

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