Clofibrate

Name: Clofibrate
Brand: Tocris Bioscience
SKU: 0824

Tocris Bioscience, part of Bio-Techne | Catalog # 0824

Citations (3)

COA / SDS

PPAR agonist

Discontinued Product

0824 has been discontinued. View all Non-selective PPAR Receptor Agonists products.

Key Product Details

Description:	PPAR agonist
Chemical Name:	Ethyl 2-(4-chlorophenoxy)-2-methylpropionate
Molecular Weight:	242.7017

View Full Technical Details for Clofibrate

Technical Data
Citations

Biological Activity for Clofibrate

Clofibrate is a PPAR agonist (EC₅₀ values are 50, 500 and > 100 μM at PPARα, PPARγ and PPARδ respectively). Antihyperlipoproteinemic.

Technical Data for Clofibrate

M. Wt	242.7017
Formula	C₁₂H₁₅ClO₃
Storage	Store at RT
CAS Number	637-07-0
PubChem ID	2796
InChi Key	KNHUKKLJHYUCFP-UHFFFAOYSA-N
Smiles	ClC1=CC=C(OC(C)(C)C(OCC)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Clofibrate

References are publications that support the biological activity of the product.

Shepherd Mechanism of action of fibrates. Postgrad.Med.J. 1993 PMID: 8497455
Willson The PPARs: from orphan receptors to drug discovery. J.Med.Chem. 2000 PMID: 10691680
Bishop-Bailey Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 2000 PMID: 10696077

Product Documents for Clofibrate

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

SDS

⚠ WARNING: This product can expose you to chemicals including Clofibrate, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov