CJ 033466

Name: CJ 033466
Brand: Tocris Bioscience
SKU: 3089

Tocris Bioscience, part of Bio-Techne | Catalog # 3089

COA / SDS

Selective 5-HT4 partial agonist

Discontinued Product

3089 has been discontinued. View all 5-HT4 Receptor Agonists products.

Key Product Details

Description:	Selective 5-HT₄ partial agonist
Chemical Name:	5-Amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)-4-piperidinyl]methyl]-imidazo[1,2-a]pyridine-8-carboxamide
Purity:	≥98% (HPLC)
Molecular Weight:	377.91

View Full Technical Details for CJ 033466

Technical Data
Citations

Biological Activity for CJ 033466

CJ 033466 is a potent and selective 5-HT₄ partial agonist (EC₅₀= 0.927 nM). Displays > 1000-fold selectivity for 5-HT₄ over other 5-HT and D₂ receptors. Exhibits gastroprokinetic effects in vivo following oral administration. Weakly blocks hERG (IC₅₀ = 2.6 μM).

Technical Data for CJ 033466

M. Wt	377.91
Formula	C₁₉H₂₈ClN₅O
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	519148-48-2
PubChem ID	10429706
InChi Key	ISKHMDNIWXPUGR-UHFFFAOYSA-N
Smiles	ClC2=C(N)N1C(C(C(NCC3CCN(CC(C)C)CC3)=O)=C2)=NC(C)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for CJ 033466

References are publications that support the biological activity of the product.

Mikami 5-Amino-6-chloro-N-[(1-isobutylpiperidin-4-yl)methyl]-2-methylimidazo[1,2-α]pyridine-8-carboxamide (CJ-033,466), a novel and selective 5-hydroxytryptamine4 receptor partial agonist: pharmacological profile in vitro and gastroproki J.Pharmacol.Exp.Ther. 2008 PMID: 18198343
Toga The 5-HT⁴ agonists cisapride, mosapride, and CJ-033466, a novel potent compound, exhibit different human ether-a-go-go-related gene (hERG)-blocking activities. J.Pharmacol.Sci. 2007 PMID: 17928736

CJ 033466

Tocris Bioscience, part of Bio-Techne | Catalog # 3089

Key Product Details

Biological Activity for CJ 033466

Technical Data for CJ 033466

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for CJ 033466

Product Documents for CJ 033466

COA

Certificate of Analysis

SDS

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