cis VH 298
Tocris Bioscience, part of Bio-Techne | Catalog # 6157
Negative control for VH 298
Product Description
cis VH 298 is a negative control for VH 298 (Cat.No. 6156). Exhibits no detectable binding of VHL.Licensing Information
Sold under licence from the University of DundeeExternal Portal Information
Chemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of VH 298 is reviewed on the chemical probes website.Product Specifications
Molecular Weight
523.65
Formula
C27H33N5O4S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(2S,4S)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CAS Number
2097381-86-5
PubChem ID
127021044
InChI Key
NDVQUNZCNAMROD-JAXLGGSGSA-N
SMILES
O=C(N[C@@H](C(C)(C)C)C(N1C[C@H](C[C@H]1C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)O)=O)C4(C#N)CC4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 52.37 | 100 | |
| Ethanol | 52.37 | 100 |
Preparing Stock Solutions
for cis VH 298
The following data is based on the product molecular weight 523.65
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.91 mL | 9.55 mL | 19.10 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.82 mL |
| 10 mM | 0.19 mL | 0.95 mL | 1.91 mL |
| 50 mM | 0.04 mL | 0.19 mL | 0.38 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Frost Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nat.Commun. 2016 PMID: 27811928
Product Specific Notices for cis VH 298
For research use only
Loading...
Loading...