Cilostazol
Tocris Bioscience, part of Bio-Techne | Catalog # 1692
PDE3A inhibitor. Also adenosine uptake inhibitor
Discontinued Product
1692 has been discontinued.
View all Phosphodiesterase Inhibitors products.
Key Product Details
Description
PDE3A inhibitor. Also adenosine uptake inhibitor
Product Description
Cilostazol is a potent phosphodiesterase III A (PDE3A) inhibitor (IC50 = 0.2 μM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.Product Specifications
Molecular Weight
369.47
Formula
C20H27N5O2
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS Number
73963-72-1
PubChem ID
2754
InChI Key
RRGUKTPIGVIEKM-UHFFFAOYSA-N
SMILES
O=C1CCC2=CC(OCCCCC3=NN=NN3C3CCCCC3)=CC=C2N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 18.47 | 50 | |
| Ethanol | 3.69 | 10 |
Preparing Stock Solutions
for Cilostazol
The following data is based on the product molecular weight 369.47
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 5.41 mL | 27.07 mL | 54.13 mL |
| 2.5 mM | 1.08 mL | 5.41 mL | 10.83 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
| 25 mM | 0.11 mL | 0.54 mL | 1.08 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Shintani General pharmacological properties of cilostazol, a new antithrombotic drug. Part I: effects on the central nervous system. Arzneimittelforschung 1985 PMID: 4074429
- Shintani General pharmacological properties of cilostazol, a new antithrombotic drug. Part II: effects on the peripheral organs. Arzneimittelforschung 1985 PMID: 3000392
- Schror The pharmacology of cilos. Diabetes Obes.Metab. 2002 PMID: 12180353
Product Specific Notices for Cilostazol
For research use only
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