CID 1375606

Name: CID 1375606
Brand: Tocris Bioscience
SKU: 6544

Tocris Bioscience, part of Bio-Techne | Catalog # 6544

COA / SDS

GPR27 agonist

Key Product Details

Description:	GPR27 agonist
Chemical Name:	2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide
Purity:	≥98% (HPLC)
Molecular Weight:	385.24

View Full Technical Details for CID 1375606

Technical Data
Citations

Biological Activity for CID 1375606

CID 1375606 is a GPR27 agonist. Promotes recruitment of β-arrestin 2 to chimeric GPR27V₂ and wild-type GPR27 in a firefly luciferase complementation assay (pEC₅₀ values are 6.34 and 5.1, respectively).

Compound Libraries for CID 1375606

CID 1375606 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for CID 1375606

M. Wt	385.24
Formula	C₂₀H₁₄Cl₂N₂O₂
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	313493-80-0
PubChem ID	1375606
InChi Key	PFHDXBXPRBQVAV-UHFFFAOYSA-N
Smiles	ClC1=CC(Cl)=C(C(NC2=CC=C(C(NC3=CC=CC=C3)=O)C=C2)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CID 1375606

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	38.52	100

Preparing Stock Solutions for CID 1375606

The following data is based on the product molecular weight 385.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.60 mL	12.98 mL	25.96 mL
5 mM	0.52 mL	2.60 mL	5.19 mL
10 mM	0.26 mL	1.30 mL	2.60 mL
50 mM	0.05 mL	0.26 mL	0.52 mL

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References for CID 1375606

References are publications that support the biological activity of the product.

Dupuis Activation of the orphan G protein-coupled receptor GPR27 by surrogate ligands promotes β-arrestin 2 recruitment. Mol.Pharmacol. 2017 PMID: 28314853