CGRP (rat)

Name: CGRP (rat)
Brand: Tocris Bioscience
SKU: 1161

Tocris Bioscience, part of Bio-Techne | Catalog # 1161

Citations (21)

COA / SDS

Potent vasodilator

Key Product Details

Description:	Potent vasodilator
Alternative Names:	Calcitonin Gene-Related Peptide (rat)
Purity:	≥95% (HPLC)
Molecular Weight:	3807

View Full Technical Details for CGRP (rat)

Technical Data
Citations

Biological Activity for CGRP (rat)

CGRP (rat) is an endogenous neuropeptide; potent vasodilator which also exerts cardiovascular, pro-inflammatory and metabolic effects.

Technical Data for CGRP (rat)

M. Wt	3807
Formula	C₁₆₂H₂₆₂N₅₀O₅₂S₂
Single Letter Sequence	SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF (Modifications: Disulfide bridge: 2-7, Phe-37 = C-terminal amide)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	83651-90-5
PubChem ID	90479760
InChi Key	SVAGNGUJZNLSEY-TYNJZYKVSA-N
Smiles	[H]N[C@@H](CO)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CGRP (rat)

Solubility

Soluble to 0.8mg/ml in water

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References for CGRP (rat)

References are publications that support the biological activity of the product.

Salim Calcitonin gene-related peptide potentiates nicotinic acetylcholine receptor-operated slow Ca²⁺ mobilization at mouse muscle endplates. Br.J.Pharmacol. 1998 PMID: 9786499
Poyner Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 1995 PMID: 8578616
Morris Isolation and characterization of human calcitonin gene-related peptide. Nature 1984 PMID: 6609312
Nakamura Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs. Brain Res. 1998 PMID: 9757038
Brain Calcitonin gene-related peptide is a potent vasodilator. Nature 1985 PMID: 3917554