CGRP (rat)

Name: CGRP (rat)
Brand: Tocris Bioscience
SKU: 1161

Tocris Bioscience, part of Bio-Techne | Catalog # 1161

Citations (18)

COA / SDS

Potent vasodilator

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Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Potent vasodilator

Alternative Names

Calcitonin Gene-Related Peptide (rat)

View all Calcitonin and Related Receptor Agonists »

Product Description

CGRP (rat) is an endogenous neuropeptide; potent vasodilator which also exerts cardiovascular, pro-inflammatory and metabolic effects.

Product Specifications

Molecular Weight

3807.00

Formula

C₁₆₂H₂₆₂N₅₀O₅₂S₂

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

83651-90-5

PubChem ID

90479760

InChI Key

SVAGNGUJZNLSEY-TYNJZYKVSA-N

SMILES

[H]N[C@@H](CO)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC1=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 0.8mg/ml in water

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

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Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

Background References

References are publications that support the biological activity of the product.

Salim Calcitonin gene-related peptide potentiates nicotinic acetylcholine receptor-operated slow Ca²⁺ mobilization at mouse muscle endplates. Br.J.Pharmacol. 1998 PMID: 9786499
Poyner Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 1995 PMID: 8578616
Morris Isolation and characterization of human calcitonin gene-related peptide. Nature 1984 PMID: 6609312
Nakamura Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs. Brain Res. 1998 PMID: 9757038
Brain Calcitonin gene-related peptide is a potent vasodilator. Nature 1985 PMID: 3917554