CGP 20712 dihydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1024

Highly potent and selective β1 antagonist
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Key Product Details

Description

Highly potent and selective β1 antagonist

View all Adrenergic beta-1 Receptor Antagonists »

Product Description

CGP 20712 dihydrochloride is a highly selective and potent β1-adrenoceptor antagonist (IC50 = 0.7 nM). Displays 10,000-fold selectivity over β2-adrenoceptors.

Product Specifications

Molecular Weight

567.39

Formula

C23H25F3N4O5.2HCl

Storage

Store at +4°C

Purity

≥96% (HPLC)

Chemical Name

1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]-2-propanol dihydrochloride

CAS Number

1216905-73-5

PubChem ID

56972164

InChI Key

PURFQCFKYNMIQF-UHFFFAOYSA-N

SMILES

Cl.Cl.CN1C=C(N=C1C1=CC=C(OCC(O)CNCCOC2=CC=C(O)C(=C2)C(N)=O)C=C1)C(F)(F)F

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 24.72 50

Preparing Stock Solutions for CGP 20712 dihydrochloride

The following data is based on the product molecular weight 567.39

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.52 mL 17.62 mL 35.25 mL
2.5 mM 0.70 mL 3.52 mL 7.05 mL
5 mM 0.35 mL 1.76 mL 3.52 mL
25 mM 0.07 mL 0.35 mL 0.70 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for CGP 20712 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CGP 20712 dihydrochloride

For research use only

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