CDP 840 hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 3936

Potent and selective PDE4 inhibitor
Discontinued Product
3936 has been discontinued. View all Phosphodiesterase Inhibitors products.

Key Product Details

Description

Potent and selective PDE4 inhibitor

View all Phosphodiesterase Inhibitors »

Product Description

CDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase (PDE) 4 (IC50 = 12 nM for native PDE4). Competitively inhibits all PDE4 isoenzymes (IC50 values are 4, 9, 9 and 45 nM for PDE4A, PDE4B, PDE4C and PDE4D human recombinant isoforms expressed in yeast).

Product Specifications

Molecular Weight

409.95

Formula

C25H27NO2.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

4-[(2R)-2-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-phenylethyl]-pyridine hydrochloride

PubChem ID

89809670

InChI Key

DQXFOLCDYKWSIT-GNAFDRTKSA-N

SMILES

COC1=C(OC2CCCC2)C=C([C@@H]([C@]4=CC=CC=C4)CC3=CC=NC=C3)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.99 100

Preparing Stock Solutions for CDP 840 hydrochloride

The following data is based on the product molecular weight 409.95

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.44 mL 12.20 mL 24.39 mL
5 mM 0.49 mL 2.44 mL 4.88 mL
10 mM 0.24 mL 1.22 mL 2.44 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for CDP 840 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CDP 840 hydrochloride

For research use only

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