CCG 50014

Tocris Bioscience, part of Bio-Techne | Catalog # 4567

Potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein
Discontinued Product
4567 has been discontinued. View all Regulators of G Protein Signaling (RGS) Inhibitors products.

Key Product Details

Description

Potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein

View all Regulators of G Protein Signaling (RGS) Inhibitors »

Product Description

CCG 50014 is a potent and selective inhibitor of regulator of G-protein signaling 4 (RGS4) protein (IC50 values are 30.1 nM and 11.0 μM for RGS4 and RGS8 respectively). Exhibits >20-fold selectivity for RGS4 over other RGS proteins.

Product Specifications

Molecular Weight

316.35

Formula

C16H13FN2O2S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione

CAS Number

883050-24-6

PubChem ID

2733079

InChI Key

QUIIIYITNGOFEI-UHFFFAOYSA-N

SMILES

FC(C=C3)=CC=C3CN(C(N(C2=CC=C(C)C=C2)S1)=O)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 31.64 100

Preparing Stock Solutions for CCG 50014

The following data is based on the product molecular weight 316.35

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.16 mL 15.81 mL 31.61 mL
5 mM 0.63 mL 3.16 mL 6.32 mL
10 mM 0.32 mL 1.58 mL 3.16 mL
50 mM 0.06 mL 0.32 mL 0.63 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for CCG 50014

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CCG 50014

For research use only

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