Calcitonin (human)

Name: Calcitonin (human)
Brand: Tocris Bioscience
SKU: 6031

Tocris Bioscience, part of Bio-Techne | Catalog # 6031

COA / SDS

Endogenous calcitonin agonist; inhibits bone resorption

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Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Endogenous calcitonin agonist; inhibits bone resorption

View all Calcitonin and Related Receptor Agonists »

Product Description

Calcitonin (human) is an endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.

Product Specifications

Molecular Weight

3417.87

Formula

C₁₅₁H₂₂₆N₄₀O₄₅S₃

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

21215-62-3

PubChem ID

122705992

InChI Key

LCQDOKHKNORMTQ-JKQNMTHDSA-N

SMILES

[H]N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CNC1=O)[C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

Bower and Hay Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development. Br.J.Pharmacol. 2016 PMID: 27061187
Lee Calcitonin and amylin receptor peptide interaction mechanisms. J.Biol.Chem. 2016 PMID: 27474777
Foster Calcitonin. A review of experimental and clinical investigations. Postgrad.Med.J. 1968 PMID: 4871775