BRD 4770

Name: BRD 4770
Brand: Tocris Bioscience
SKU: 6282

Tocris Bioscience, part of Bio-Techne | Catalog # 6282

COA / SDS

G9a inhibitor and S-adenosyl methionine mimetic; cell permeable

Discontinued Product

6282 has been discontinued. View all G9a/GLP Inhibitor products.

Key Product Details

Description:	G9a inhibitor and S-adenosyl methionine mimetic; cell permeable
Chemical Name:	Methyl-2-(benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylate
Purity:	≥98% (HPLC)
Molecular Weight:	413.47

View Full Technical Details for BRD 4770

Technical Data
Citations

Biological Activity for BRD 4770

BRD 4770 is a G9a inhibitor and S-adenosyl methionine (SAM) mimetic. Inhibits methylation of H3K9 (EC₅₀ ~ 5 μM) and induces senescence in PANC-1 cells. Induces ATM activation without DNA damage. Cell permeable.

Technical Data for BRD 4770

M. Wt	413.47
Formula	C₂₅H₂₃N₃O₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	1374601-40-7
PubChem ID	72193870
InChi Key	UCGWYCMPZXDHNR-UHFFFAOYSA-N
Smiles	COC(C1=CC=C2N(C(NC(C3=CC=CC=C3)=O)=NC2=C1)CCCC4=CC=CC=C4)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for BRD 4770

References are publications that support the biological activity of the product.

Yuan A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma. ACS Chem.Biol. 2012 PMID: 22536950

BRD 4770

Tocris Bioscience, part of Bio-Techne | Catalog # 6282

Key Product Details

Biological Activity for BRD 4770

Technical Data for BRD 4770

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for BRD 4770

Product Documents for BRD 4770

COA

Certificate of Analysis

SDS

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