BML 111
Tocris Bioscience, part of Bio-Techne | Catalog # 5488
FPR2 (lipoxin A4 receptor) agonist
Key Product Details
Description
FPR2 (lipoxin A4 receptor) agonist
Product Description
BML 111 is a FPR2 (lipoxin A4 receptor) agonist. Suppresses tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. Also protects against hemorrhagic shock-induced acute lung injury in rats. Lipoxin A4 analog.Product Specifications
Molecular Weight
192.21
Formula
C8H16O5
Storage
Store at -20°C
Chemical Name
(5S,6R)-Methyl 5,6,7-trihydroxyheptanoate
CAS Number
78606-80-1
PubChem ID
10899465
InChI Key
RNMFWAFZUNVQOR-NKWVEPMBSA-N
SMILES
OC[C@@H](O)[C@@H](O)CCCC(OC)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 19.22 | 100 | |
| DMSO | 19.22 | 100 |
Preparing Stock Solutions
for BML 111
The following data is based on the product molecular weight 192.21
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.20 mL | 26.01 mL | 52.03 mL |
| 5 mM | 1.04 mL | 5.20 mL | 10.41 mL |
| 10 mM | 0.52 mL | 2.60 mL | 5.20 mL |
| 50 mM | 0.10 mL | 0.52 mL | 1.04 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Gong BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats. Resuscitation. 2012 PMID: 22245750
- Chen Lipoxin A4 and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis. Mol.Cancer.Ther. 2010 PMID: 20682645
Product Specific Notices for BML 111
For research use only
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