BIX

Name: BIX
Brand: Tocris Bioscience
SKU: 5375

Tocris Bioscience, part of Bio-Techne | Catalog # 5375

COA / SDS

BiP (Hsp70-5) ER chaperone inducer

Discontinued Product

5375 has been discontinued. View all HSP70 Modulators products.

Key Product Details

Description:	BiP (Hsp70-5) ER chaperone inducer
Chemical Name:	2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid
Purity:	≥98% (HPLC)
Molecular Weight:	209.22

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Technical Data
Citations

Biological Activity for BIX

BIX is a BiP (Hsp70-5) ER chaperone inducer; induces BiP expression in vitro and in vivo. Protects against ER-stress induced cell death in neuronal and retinal cell lines. Also protects against ischaemia-induced hippocampal cell death in vivo.

Technical Data for BIX

M. Wt	209.22
Formula	C₉H₇NO₃S
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	101714-41-4
PubChem ID	16656807
InChi Key	SVFLBLCWKKQKDW-UHFFFAOYSA-N
Smiles	O=C(CSC#N)C1=CC=C(O)C(O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for BIX

References are publications that support the biological activity of the product.

Oida Induction of BiP, an ER-resident protein, prevents the neuronal death induced by transient forebrain ischemia in gerbil. Brain Res. 2008 PMID: 18395193
Kudo A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ. 2008 PMID: 18049481
Inokuchi Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death. Invest.Ophthalmol.Vis.Sci. 2009 PMID: 18757512

BIX

Tocris Bioscience, part of Bio-Techne | Catalog # 5375

Key Product Details

Biological Activity for BIX

Technical Data for BIX

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for BIX

Product Documents for BIX

COA

Certificate of Analysis

SDS

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