BF 738735

Name: BF 738735
Brand: Tocris Bioscience
SKU: 6246

Tocris Bioscience, part of Bio-Techne | Catalog # 6246

Citations (2)

COA / SDS

Potent and selective PI 4-kinase IIIβ inhibitor; broad spectrum enterovirus replication inhibitor

Discontinued Product

6246 has been discontinued. View all Other Kinase Inhibitors products.

Key Product Details

Description:	Potent and selective PI 4-kinase IIIβ inhibitor; broad spectrum enterovirus replication inhibitor
Chemical Name:	2-Fluoro-4-[2-methyl-8-[[[3-(methylsulfonyl)phenyl]methyl]amino]imidazo[1,2-a]pyrazin-3-yl]phenol
Purity:	≥98% (HPLC)
Molecular Weight:	426.47

View Full Technical Details for BF 738735

Technical Data
Citations

Biological Activity for BF 738735

BF 738735 is a potent and selective ATP-competitive phosphatidylinositol 4-kinase III beta (PI 4-KIIIβ) inhibitor (IC₅₀ = 5.7 nM). Displays approximately 200-fold selectivity over PI 4-KIIIα. Broad spectrum enterovirus replication inhibitor.

Technical Data for BF 738735

M. Wt	426.47
Formula	C₂₁H₁₉FN₄O₃S
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1436383-95-7
PubChem ID	135742054
InChi Key	IMHZCCZYPHJVMS-UHFFFAOYSA-N
Smiles	CC1=C(C2=CC(F)=C(C=C2)O)N3C=CN=C(C3=N1)NCC4=CC(S(C)(=O)=O)=CC=C4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for BF 738735

References are publications that support the biological activity of the product.

van der Schaar A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase III. Antimicrob.Agents Chemother.
MacLeod Identification of a series of compounds with potent antiviral activity for the treatment of enterovirus infections. ACS Med.Chem.Lett. 2013 PMID: 24900715

BF 738735

Tocris Bioscience, part of Bio-Techne | Catalog # 6246

Key Product Details

Biological Activity for BF 738735

Technical Data for BF 738735

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for BF 738735

Product Documents for BF 738735

COA

Certificate of Analysis

SDS

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