BETP

Tocris Bioscience, part of Bio-Techne | Catalog # 4778

Positive allosteric modulator of GLP-1 receptors
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Key Product Details

Description

Positive allosteric modulator of GLP-1 receptors

View all Glucagon-Like Peptide 1 Receptor Modulators »

Product Description

BETP is a selective positive allosteric modulator and partial agonist of the glucagon-like peptide 1 (GLP-1) receptor. Increases binding affinity of oxyntomodulin for the GLP-1 receptor. Potentiates oxyntomodulin-mediated GLP-1 receptor signaling in vitro and insulin secretion in vivo. Has no effect on GLP-2, GIP, PTH or glucagon receptors.

Product Specifications

Molecular Weight

406.42

Formula

C20H17F3N2O2S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-(Ethylsulfinyl)-4-[3-(phenylmethoxy)phenyl]-6-(trifluoromethyl)pyrimidine

CAS Number

1371569-69-5

PubChem ID

49868481

InChI Key

NTDFYGSSDDMNHI-UHFFFAOYSA-N

SMILES

CCS(C1=NC(C2=CC=CC(OCC3=CC=CC=C3)=C2)=CC(C(F)(F)F)=N1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.64 100
Ethanol 20.32 50

Preparing Stock Solutions for BETP

The following data is based on the product molecular weight 406.42

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.46 mL 12.30 mL 24.61 mL
5 mM 0.49 mL 2.46 mL 4.92 mL
10 mM 0.25 mL 1.23 mL 2.46 mL
50 mM 0.05 mL 0.25 mL 0.49 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Product Documents for BETP

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BETP

For research use only

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