Bax inhibitor peptide V5

Name: Bax inhibitor peptide V5
Brand: Tocris Bioscience
SKU: 1785

Tocris Bioscience, part of Bio-Techne | Catalog # 1785

Citations (12)

COA / SDS

Inhibitor of Bax-mediated apoptosis

Discontinued Product

1785 has been discontinued. View all Bcl-2 Family Inhibitors products.

Key Product Details

Description:	Inhibitor of Bax-mediated apoptosis
Molecular Weight:	586.79

View Full Technical Details for Bax inhibitor peptide V5

Technical Data
Citations

Biological Activity for Bax inhibitor peptide V5

Bax inhibitor peptide V5 is a cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. Designed based on the Bax-binding domain of human Ku70. Inhibits Bax-mediated apoptosis in vitro. Shown to inhibit anti-cancer drug-induced apoptosis in vitro.

Control Peptide also available.

Licensing Information

Sold under license

Technical Data for Bax inhibitor peptide V5

M. Wt	586.79
Formula	C₂₇H₅₀N₆O₆S
Single Letter Sequence	VPMLK
Storage	Desiccate at -20°C
CAS Number	579492-81-2
PubChem ID	10129115
InChi Key	NHMUTADCTDDWPV-YFNVTMOMSA-N
Smiles	[H]N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Bax inhibitor peptide V5

References are publications that support the biological activity of the product.

Yoshida Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem.Biophys.Res.Commun. 2004 PMID: 15358121
Sawatzky The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo. Am.J.Pathol. 2006 PMID: 16400007