Autocamtide-2-related inhibitory peptide
Tocris Bioscience, part of Bio-Techne | Catalog # 1688
Selective CaM kinase II inhibitor
Key Product Details
Description
Selective CaM kinase II inhibitor
Alternative Names
AIP
Product Description
Autocamtide-2-related inhibitory peptide is a selective and potent calmodulin-dependent protein kinase II (CaM kinase II) inhibitor (IC50 = 40 nM). Selective over PKC, PKA and CaM kinase IV (IC50 > 10 μM).Cell permeable derivative also available.
Product Specifications
Molecular Weight
1497.76
Formula
C64H116N22O19
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
167114-91-2
PubChem ID
25031982
InChI Key
USSJDGBHUQEJJG-HKDQSZHBSA-N
SMILES
[H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ishida and Fujisawa Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain. J.Biol.Chem. 1995 PMID: 7836445
- Takasawa Requirement of calmodulin-dependent protein kinase II in cyclic ADP-ribose-mediated intracellular Ca2+ mobilization. J.Biol.Chem. 1995 PMID: 8530441
- Ishida A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem.Biophys.Res.Commun. 1995 PMID: 7626114
Product Specific Notices for Autocamtide-2-related inhibitory peptide
For research use only
Loading...
Loading...