ATPγS tetralithium salt

Name: ATPγS tetralithium salt
Brand: Tocris Bioscience
SKU: 4080

Tocris Bioscience, part of Bio-Techne | Catalog # 4080

Citations (28)

COA / SDS

Non-selective P2 agonist; analog of ATP (Cat. No. 3245)

Key Product Details

Description:	Non-selective P2 agonist; analog of ATP (Cat. No. 3245)
Alternative Names:	ATP-γS
Chemical Name:	Adenosine-5'-(γ-thio)-triphosphate tetralithium salt
Purity:	≥85% (HPLC)
Molecular Weight:	546.98

View Full Technical Details for ATPγS tetralithium salt

Technical Data
Citations

Biological Activity for ATPγS tetralithium salt

ATPγS tetralithium salt is a P2 purinergic receptor agonist. Nonhydrolyzable analog of ATP (Cat. No. 3245).

Technical Data for ATPγS tetralithium salt

M. Wt	546.98
Formula	C₁₀H₁₂Li₄N₅O₁₂P₃S
Storage	Store at -20°C
Purity	≥85% (HPLC)
CAS Number	93839-89-5
PubChem ID	5311341
InChi Key	DWQFDOIBOYDYKH-KWIZKVQNSA-J
Smiles	NC1=C2C(N([C@@H]3O[C@H](COP(OP(OP([O-])([O-])=S)([O-])=O)([O-])=O)[C@@H](O)[C@H]3O)C=N2)=NC=N1.[Li+].[Li+].[Li+].[Li+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for ATPγS tetralithium salt

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	27.35	50

Preparing Stock Solutions for ATPγS tetralithium salt

The following data is based on the product molecular weight 546.98.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	3.66 mL	18.28 mL	36.56 mL
2.5 mM	0.73 mL	3.66 mL	7.31 mL
5 mM	0.37 mL	1.83 mL	3.66 mL
25 mM	0.07 mL	0.37 mL	0.73 mL

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References for ATPγS tetralithium salt

References are publications that support the biological activity of the product.

Peck and Herschlag Adenosine 5'-O-(3-thio)triphosphate (ATPgammaS) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor elF4A. RNA 2003 PMID: 13130132
Chrysogelos The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate). J.Biol.Chem. 1983 PMID: 6313668
Evans Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2X purinoceptors). Mol.Pharmacol. 1995 PMID: 7544432