Anpirtoline hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0703

Highly potent 5-HT1B agonist; also 5-HT3 antagonist
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Key Product Details

Description

Highly potent 5-HT1B agonist; also 5-HT3 antagonist

View all 5-HT1B Receptor Agonists »

Product Description

Anpirtoline hydrochloride is a highly potent 5-HT1B receptor agonist (Ki values are 28, 150 and 1490 nM at 5-HT1B, 5-HT1A and 5-HT2 receptors respectively). Decreases central serotonin synthesis and attenuates aggressive behavior in vivo. Also acts as an antagonist at 5-HT3 receptors (Ki = 29.5 nM) and is brain penetrant.

Product Specifications

Molecular Weight

265.20

Formula

C10H13ClN2S.HCl

Storage

Desiccate at +4°C

Purity

≥99% (HPLC)

Chemical Name

6-Chloro-2-[piperidinyl-4-thio]pyridine hydrochloride

CAS Number

99201-87-3

PubChem ID

6917943

InChI Key

GRXDJABVNGUGCW-UHFFFAOYSA-N

SMILES

Cl.ClC1=NC(SC2CCNCC2)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100
DMSO 26.52 100

Preparing Stock Solutions for Anpirtoline hydrochloride

The following data is based on the product molecular weight 265.20

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.77 mL 18.85 mL 37.71 mL
5 mM 0.75 mL 3.77 mL 7.54 mL
10 mM 0.38 mL 1.89 mL 3.77 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

Calculators

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Product Documents for Anpirtoline hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Anpirtoline hydrochloride

For research use only

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