Alprenolol hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 2806
β antagonist; also 5-HT1A antagonist
Key Product Details
Description
β antagonist; also 5-HT1A antagonist
Product Description
Alprenolol hydrochloride is a β-adrenoceptor (β2 > β1 > β3) and 5-HT1A receptor antagonist.Product Specifications
Molecular Weight
285.81
Formula
C15H23NO2.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol hydrochloride
CAS Number
13707-88-5
PubChem ID
66368
InChI Key
RRCPAXJDDNWJBI-UHFFFAOYSA-N
SMILES
C=CCC1=CC=CC=C1OCC(O)CNC(C)C.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 28.58 | 100 |
Preparing Stock Solutions
for Alprenolol hydrochloride
The following data is based on the product molecular weight 285.81
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.50 mL | 17.49 mL | 34.99 mL |
| 5 mM | 0.70 mL | 3.50 mL | 7.00 mL |
| 10 mM | 0.35 mL | 1.75 mL | 3.50 mL |
| 50 mM | 0.07 mL | 0.35 mL | 0.70 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bjorvatin The 5-HT1A antagonist (-)-alprenolol fails to modify sleep or zimeldine-induced sleep-waking effects in rats. Pharmacol.Biochem.Behav. 1992 PMID: 1388278
- Baker The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br.J.Pharmacol. 2005 PMID: 15655528
- Blue Antagonist characterization of atypical beta adrenoceptors in guinea pig ileum: blockade by alprenolol and dihydroalprenolol. J.Pharmacol.Exp.Ther. 1990 PMID: 1969469
Product Specific Notices for Alprenolol hydrochloride
For research use only
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