α-Methyl-5-hydroxytryptamine maleate
Tocris Bioscience, part of Bio-Techne | Catalog # 0557
5-HT2B agonist
Discontinued Product
0557 has been discontinued.
View all 5-HT2B Receptor Agonists products.
Product Description
5-HT2B receptor selective agonist with pKi values of 8.4, 6.1 and 7.3 at 5-HT2B, 5-HT2A and 5-HT2C receptors respectively.Product Specifications
Molecular Weight
306.32
Formula
C11H14N2O.C4H4O4
Storage
Store at -20°C
Purity
≥98% (HPLC)
CAS Number
97469-12-0
PubChem ID
9922558
InChI Key
YQNHFSXRABPJLP-BTJKTKAUSA-N
SMILES
OC(=O)\C=C/C(O)=O.CC(N)CC1=CNC2=C1C=C(O)C=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 10 | ||
| DMSO | 30.63 | 100 |
Preparing Stock Solutions
for α-Methyl-5-hydroxytryptamine maleate
The following data is based on the product molecular weight 306.32
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.26 mL | 16.32 mL | 32.65 mL |
| 5 mM | 0.65 mL | 3.26 mL | 6.53 mL |
| 10 mM | 0.33 mL | 1.63 mL | 3.26 mL |
| 50 mM | 0.07 mL | 0.33 mL | 0.65 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Richardson Identification of serotonin M-receptor sub-types and their specific blockade by a new class of drugs. Nature 1985 PMID: 3839291
- Wilson 5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 1990 PMID: 1968974
- Baxter 5-HT2 receptor subtypes: a family re-united? TiPS 1995 PMID: 7792930
Product Specific Notices for α-Methyl-5-hydroxytryptamine maleate
For research use only
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