ACDPP hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2254

Selective mGlu5 antagonist
Discontinued Product
2254 has been discontinued. View all Group I mGluR Antagonists products.

Key Product Details

Description

Selective mGlu5 antagonist

View all Group I mGluR Antagonists »

Product Description

Antagonist at the mGlu5 receptor (Ki = 295 nM). Inhibits human mGlu5 receptor-mediated calcium flux with an IC50 of 134 nM.

Product Specifications

Molecular Weight

329.19

Formula

C12H13ClN6O.HCl

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

3-Amino-6-chloro-5-dimethylamino-N-2-pyridinylpyrazinecarboxamide hydrochloride

PubChem ID

16759168

InChI Key

CXIHLPLRTFPHKX-UHFFFAOYSA-N

SMILES

Cl.CN(C)C1=C(Cl)N=C(C(=O)NC2=CN=CC=C2)C(N)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 32.92 100

Preparing Stock Solutions for ACDPP hydrochloride

The following data is based on the product molecular weight 329.19

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.04 mL 15.19 mL 30.38 mL
5 mM 0.61 mL 3.04 mL 6.08 mL
10 mM 0.30 mL 1.52 mL 3.04 mL
50 mM 0.06 mL 0.30 mL 0.61 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for ACDPP hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ACDPP hydrochloride

For research use only

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