Ac4GlcNAlk
Tocris Bioscience, part of Bio-Techne | Catalog # 7750
Metabolic chemical reporter for studying glycosylation and glycoproteins
Key Product Details
Description
Metabolic chemical reporter for studying glycosylation and glycoproteins
Product Description
Ac4GlcNAlk is a metabolic chemical reporter (MCR) for studying cell surface glycosylation. It is used for identification of O-GlcNAc modified proteins. In cells expressing the engineered pyrophosphorylase, mut-AGX1, Ac4GlcNAlk is efficiently converted into UDP-GlcNAlk which is incorporated into GlcNAlk-containing glycoproteins.Product Specifications
Molecular Weight
427.41
Formula
C19H25NO10
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
2-Deoxy-2-[(1-oxo-4-pentyn-1-yl)amino]-D-glucopyranose-1,3,4,6-tetraacetate
CAS Number
1361993-37-4
PubChem ID
101797984
InChI Key
PODQGPKRSTUNAT-ULAPBGCESA-N
SMILES
CC(OC[C@H]1OC([C@@H]([C@H]([C@@H]1OC(C)=O)OC(C)=O)NC(CCC#C)=O)OC(C)=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 42.74 | 100 |
Preparing Stock Solutions
for Ac4GlcNAlk
The following data is based on the product molecular weight 427.41
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.34 mL | 11.70 mL | 23.40 mL |
| 5 mM | 0.47 mL | 2.34 mL | 4.68 mL |
| 10 mM | 0.23 mL | 1.17 mL | 2.34 mL |
| 50 mM | 0.05 mL | 0.23 mL | 0.47 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Cioce Optimization of metabolic oligosaccharide engineering with Ac4GalNAlk and Ac4GlcNAlk by an engineered pyrophosphorylase. ACS Chem.Biol. 2021 PMID: 33835779
Product Specific Notices for Ac4GlcNAlk
For research use only
Loading...
Loading...