AA 29504

Name: AA 29504
Brand: Tocris Bioscience
SKU: 3972

Tocris Bioscience, part of Bio-Techne | Catalog # 3972

Citations (2)

COA / SDS

Positive allosteric modulator of GABAA receptors

Discontinued Product

3972 has been discontinued. View all GABA-A Receptor Modulators products.

Key Product Details

Description:	Positive allosteric modulator of GABA_A receptors
Chemical Name:	N¹-Ethoxycarbonyl-N⁴-[(2,4,6-trimethylpheny)lmethyl]-1,2,4-triaminobenzene
Purity:	≥98% (HPLC)
Molecular Weight:	327.42

View Full Technical Details for AA 29504

Technical Data
Citations

Biological Activity for AA 29504

AA 29504 is a positive allosteric modulator of GABA_A receptors. Modulates both α₄β₃δ-containing extrasynaptic receptors and α₁β₃γ_2S-containing receptors in Xenopus oocytes, displaying a stronger modulatory effect at the former. Reduces motor coordination and exhibits anxiolytic effects in vivo.

Technical Data for AA 29504

M. Wt	327.42
Formula	C₁₉H₂₅N₃O₂
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	945828-50-2
PubChem ID	23188887
InChi Key	SCOOTUMXCXKEAD-UHFFFAOYSA-N
Smiles	NC1=C(NC(OCC)=O)C=CC(NCC2=C(C)C=C(C)C=C2C)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for AA 29504

References are publications that support the biological activity of the product.

Olander Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABA_A receptors. Biochem. Pharmacol. 2018 PMID: 29454619
Hoestgaard-Jensen Pharmacological characterization of a novel positive modulator at α₄β₃δ-containing extrasynaptic GABA_A receptors. Neuropharmacology 2010 PMID: 20060846

AA 29504

Tocris Bioscience, part of Bio-Techne | Catalog # 3972

Key Product Details

Biological Activity for AA 29504

Technical Data for AA 29504

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for AA 29504

Product Documents for AA 29504

COA

Certificate of Analysis

SDS

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