7-Chlorokynurenic acid

Tocris Bioscience, part of Bio-Techne | Catalog # 0237

Potent competitive inhibitor of L-glutamate uptake
Catalog #
Availability
Size / Price
Qty
0237/10
0237/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

Potent competitive inhibitor of L-glutamate uptake

View all Glutamate (EAAT) Transporter Inhibitors »

Product Description

7-Chlorokynurenic acid is an NMDA receptor antagonist acting at the glycine site. Potent competitive inhibitor of L-glutamate transport into synaptic vesicles.

Sodium Salt also available.

Product Specifications

Molecular Weight

223.62

Formula

C10H6ClNO3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

7-Chloro-4-hydroxyquinoline-2-carboxylic acid

CAS Number

18000-24-3

PubChem ID

1884

InChI Key

UAWVRVFHMOSAPU-UHFFFAOYSA-N

SMILES

OC(=O)C1=CC(O)=C2C=CC(Cl)=CC2=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 22.36 100

Preparing Stock Solutions for 7-Chlorokynurenic acid

The following data is based on the product molecular weight 223.62

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.47 mL 22.36 mL 44.72 mL
5 mM 0.89 mL 4.47 mL 8.94 mL
10 mM 0.45 mL 2.24 mL 4.47 mL
50 mM 0.09 mL 0.45 mL 0.89 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for 7-Chlorokynurenic acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for 7-Chlorokynurenic acid

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.