6,2',4'-Trimethoxyflavone
Tocris Bioscience, part of Bio-Techne | Catalog # 3859
Aryl hydrocarbon receptor antagonist
Discontinued Product
3859 has been discontinued.
View all Aryl Hydrocarbon Receptor Antagonists products.
Key Product Details
Description
Aryl hydrocarbon receptor antagonist
Product Description
6,2',4'-Trimethoxyflavone is an aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). Exhibits no short term agonist activity and no species or promoter dependence.Product Specifications
Molecular Weight
312.32
Formula
C18H16O5
Storage
Store at RT
Purity
≥97% (HPLC)
Chemical Name
2',4',6-Trimethoxyflavone
CAS Number
720675-74-1
PubChem ID
688802
InChI Key
WUWFDVDASNSUKP-UHFFFAOYSA-N
SMILES
O=C1C3=C(C=CC(OC)=C3)OC(C2=CC=C(OC)C=C2OC)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 1.56 | 5 with gentle warming |
Preparing Stock Solutions
for 6,2',4'-Trimethoxyflavone
The following data is based on the product molecular weight 312.32
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.05 mM | 64.04 mL | 320.18 mL | 640.37 mL |
| 0.25 mM | 12.81 mL | 64.04 mL | 128.07 mL |
| 0.5 mM | 6.40 mL | 32.02 mL | 64.04 mL |
| 2.5 mM | 1.28 mL | 6.40 mL | 12.81 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Murray Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone. J.Pharmacol.Exp.Ther. 2010 PMID: 19828881
Product Specific Notices for 6,2',4'-Trimethoxyflavone
For research use only
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