4F 4PP oxalate

Name: 4F 4PP oxalate
Brand: Tocris Bioscience
SKU: 0523

Tocris Bioscience, part of Bio-Techne | Catalog # 0523

Citations (6)

COA / SDS

Selective 5-HT2A antagonist

Discontinued Product

0523 has been discontinued. View all 5-HT2A Receptor Antagonists products.

Key Product Details

Description:	Selective 5-HT_2A antagonist
Chemical Name:	4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate
Purity:	≥99% (HPLC)
Molecular Weight:	429.49

View Full Technical Details for 4F 4PP oxalate

Technical Data
Citations

Biological Activity for 4F 4PP oxalate

4F 4PP oxalate is a selective 5-HT_2A antagonist with almost as high affinity (K_i = 5.3 nM) as Ketanserin (Cat. No. 0908) but with a much lower affinity for 5-HT_2C sites (K_i = 620 nM).

Technical Data for 4F 4PP oxalate

M. Wt	429.49
Formula	C₂₂H₂₆FNO.C₂H₂O₄
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	144734-36-1
PubChem ID	24745966
InChi Key	VUJYJCRJPFMHEM-UHFFFAOYSA-N
Smiles	OC(=O)C(O)=O.FC1=CC=C(C=C1)C(=O)C1CCN(CCCCC2=CC=CC=C2)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for 4F 4PP oxalate

References are publications that support the biological activity of the product.

Herndon Ketanserin analogues - structure affinity relationships of 5HT₂ and 5HT_1C serotonin receptor binding. J.Med.Chem. 1992 PMID: 1479590
Hagberg Stimulation of 5-HT_2A receptors on astrocytes in primary culture opens voltage-independent Ca²⁺ channels. Neurochem.Int. 1998 PMID: 9542727

4F 4PP oxalate

Tocris Bioscience, part of Bio-Techne | Catalog # 0523

Key Product Details

Biological Activity for 4F 4PP oxalate

Technical Data for 4F 4PP oxalate

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 4F 4PP oxalate

Product Documents for 4F 4PP oxalate

COA

Certificate of Analysis

SDS

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